Hospital is one of the most potential places for virus spreading especially in Emergency ward which be the patient’s transfer door of the hospital. Therefore, to avoid the Covid-19 virus spreading, well health protocol implementation is needed. The important factor in implementing health protocol process is having knowledge and attitude toward Covid-19 to lowering the number of Covid-19 cases which has been risen. The aim of this research was to find out the correlation between knowledge and attitude toward Covid-19in Emergency ward of Meuraxa Regional Public Hospital. This research used quantitative method with cross sectional design. The population of this research was 120 patient’s family in Emergency ward of Meuraxa Regional Public Hospital which were chosen by using Convenience Sampling. The research’s instrument was knowledge, attitude, and health protocol questionnaire in which it’s reability has been tested. The data were collected by distributing the questionnaire directly, while the data regarding to the health protocol were obtained by doing observation. The result of the research showed that 83.3% of the patient’s family had good knowledge regarding Covid-19, 68.3% had good attitude regarding Covid-19, and 73.3% obey the health protocol. In conclusion, there was significant correlation between knowledge and attitude regarding Covid-19 and the health protocol implementation on the patient’s family in Emergency ward of Meuraxa Regional Public Hospital. It is expected to the next researchers to conduct other researches related to the factors influence the correlation between knowledge and attitude regarding Covid-19 and the health protocol implementation.