Doctor is a profession that was need when the disaster occur. Disaster management bloc is a bloc in medical education curriculum that learn about the basics of disaster. The objective of this study is to evaluate and analyze the medical student’s knowledge and participation of Syiah Kuala University about disaster management after joined Disaster Management bloc class 2009-2011. This quantitative study was consist of 238 subjects which selected using stratified random sampling method. The data was obtained from questionnaire that consist of questions about knowledge and statements about participation in disaster management. The data was analyzed using One-way ANOVA and Chi-Square to test the hypothesis. The results shown that the students' knowledge about disaster management, good was 64.7%, moderate was 24.8% and poor knowledge was 10.5%. Based on the length of time span after studying disaster management bloc indicates that the class of 2009 had the highest knowledge which was 82.56% compared with the class of 2010 had a good knowledge was 81.68% and the class of 2011 was 75%. The participation of students towards disaster management, low was about 76.5% and high about 23.5%. The class 2009 with the longest time span after studying disaster management bloc shown average participation about 4.47%, whereas 2010 at 4.32% and the class of 2011 was 4.50%. There was no relationship between knowledge and participation about disaster management (p > 0.05). Therefore the longer span time learning about disaster management, the knowledge will better.