Faunus ater snail or commonly known as “cue” is one of the aquatic resources that has not been utilized optimally, this type of snail produces mucus which have the potential to be developed in the pharmaceutical field. This study aimed to determine the inhibition of Faunus ater snail mucus against the activity of Staphylococcus aureus bacteria. Antimicrobial potential compounds were analyzed by qualitative phytochemical test and an inhibition test was carried out by the disc diffusion method (Kirby-Bauer) by measuring diameter of the inhibition zone around the disc. This type of research is a laboratory experiment with various treatment of 5%, 10%, 15%, 20%, 25% of Faunus ater snail mucus, disk vancomycin (k+), and aquadest (k-) against Staphylococcus aureus ATCC 25923 with 3 replicates. The result of phytochemical test of Faunus ater snail mucus positive contained of alkaloid, phenolic, saponin, and tannin. The inhibition test showed that Faunus ater snail mucus could not inhibit the activity of Staphylococcus aureus bacteria (clear zone = 0 mm). Disk vancomycin (k+) had an inhibition zone of 14,35 mm and aquadest (k-) had no inhibition zone. It is concluded that Faunus ater snail mucus with various concentrations did not show any antibacterial activity.
Keywords: Antibacterial, inhibition, Faunus ater snail mucus, Staphylococcus aureus